Description

Alprazolam USP

Alprazolam USP is a high-purity, short-acting benzodiazepine used in pharmaceutical formulations for the treatment of anxiety disorders, panic disorder, and related conditions. Compliant with United States Pharmacopeia (USP) standards, it acts by enhancing the inhibitory effects of gamma-aminobutyric acid (GABA) at the GABA-A receptor, resulting in anxiolytic, sedative, and muscle-relaxant effects. Alprazolam USP
• Is a USP-compliant benzodiazepine for oral pharmaceutical formulations
• Used in the treatment of anxiety, panic disorder, and generalized anxiety conditions
• Provides rapid onset of action with short elimination half-life
• Is suitable for immediate-release, extended-release, and sublingual formulations
• Is manufactured under Good Manufacturing Practice (GMP) certified conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data
Alprazolam is chemically designated as 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine. It appears as a white to off-white crystalline powder, sparingly soluble in water, and soluble in ethanol and organic solvents, ensuring formulation flexibility across various oral dosage forms.
In pharmaceutical applications, Alprazolam USP is used in:
• Oral tablets and extended-release formulations for anxiety and panic disorders
• Sublingual or orally disintegrating tablets for rapid onset of action
• Combination therapies addressing anxiety-related depression and insomnia
• Clinical research on central nervous system pharmacology and receptor binding
• Compounded preparations requiring precise dosage and bioavailability control
Alprazolam USP acts as a positive allosteric modulator of the GABA-A receptor, enhancing chloride ion influx and neuronal hyperpolarization. This action leads to anxiolytic and sedative effects while maintaining favorable tolerability and safety when used under medical supervision.
CarboMer supplies Alprazolam USP that is characterized by assay, purity, polymorphic form, and residual solvents. The material meets USP monograph specifications and is suitable for regulated pharmaceutical manufacturing.
The material is packaged in sealed, moisture-protective, tamper-evident containers. It is available in laboratory, pilot, and commercial-scale volumes. Minimum order quantities (MOQ), lead times, and documentation including CoA and SDS are provided upon request.
Each batch is tested for identity (IR, HPLC), assay (anhydrous basis), residual solvents, melting point, and microbial limits. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.
As with all CarboMer central nervous system APIs, Alprazolam USP is supported by formulation expertise, regulatory guidance, and reliable global supply to ensure safe, effective, and compliant pharmaceutical products.