Description

Etofibrate

Etofibrate is a high-purity lipid-regulating agent used in pharmaceutical formulations and clinical research for the management of dyslipidemia, particularly elevated triglycerides and mixed hyperlipidemia. It is a prodrug composed of Clofibrate and Nicotinic Acid linked via an ester bond, designed to provide combined lipid-lowering effects with improved tolerability.
Etofibrate is chemically designated as 2-(4-Chlorophenoxy)-2-methylpropionic acid 2-(pyridin-3-ylcarbonyl)oxyethyl ester. It appears as a white to off-white crystalline powder that is practically insoluble in water and soluble in organic solvents, supporting formulation into oral solid dosage forms.
In pharmaceutical and research applications, Etofibrate is used in:
• Oral tablets and capsules for lipid-lowering therapy
• Treatment of hypertriglyceridemia and mixed dyslipidemia
• Combination lipid-management strategies
• Research involving fibrate pharmacology and lipid metabolism
• Studies focused on prodrug design and metabolic activation
Etofibrate is hydrolyzed in vivo to release Clofibrate and Nicotinic Acid, which act synergistically to reduce serum triglycerides, total cholesterol, and very-low-density lipoproteins. This dual-action mechanism supports effective lipid regulation while moderating adverse effects associated with individual agents.
CarboMer supplies Etofibrate with details of assay, purity, residual solvents, particle size, and microbial quality. The material is suitable for regulated pharmaceutical development and clinical research applications.
The material is packaged in sealed, moisture-resistant, tamper-evident containers. Available in laboratory, pilot, and commercial-scale quantities. Documentation includes Certificate of Analysis (CoA), Safety Data Sheet (SDS), and complete traceability.
Each batch is tested for identity (IR, HPLC), assay, impurity profile, water content, and microbial limits. Technical support is available to assist with formulation considerations and regulatory compliance.
As with all CarboMer supplied lipid-regulating active ingredients, Etofibrate is supported by dependable global supply, rigorous quality control, and expert technical guidance to ensure consistent and reliable pharmaceutical product development.